Close Menu
  • Home
  • AI
  • Big Data
  • Cloud Computing
  • iOS Development
  • IoT
  • IT/ Cybersecurity
  • Tech
    • Nanotechnology
    • Green Technology
    • Apple
    • Software Development
    • Software Engineering

Subscribe to Updates

Get the latest technology news from Bigteetechhub about IT, Cybersecurity and Big Data.

    What's Hot

    GitLab Extends Agentic AI with New Automated Security Remediation, Pipeline Setup, and Delivery Analytics

    April 19, 2026

    AI’s impact on apparel beyond forecasting and fit

    April 19, 2026

    Enhancing antitumour nanovaccine efficacy via integrated cholesterol modulation in situ

    April 19, 2026
    Facebook X (Twitter) Instagram
    Facebook X (Twitter) Instagram
    Big Tee Tech Hub
    • Home
    • AI
    • Big Data
    • Cloud Computing
    • iOS Development
    • IoT
    • IT/ Cybersecurity
    • Tech
      • Nanotechnology
      • Green Technology
      • Apple
      • Software Development
      • Software Engineering
    Big Tee Tech Hub
    Home»Nanotechnology»Enhancing antitumour nanovaccine efficacy via integrated cholesterol modulation in situ
    Nanotechnology

    Enhancing antitumour nanovaccine efficacy via integrated cholesterol modulation in situ

    big tee tech hubBy big tee tech hubApril 19, 2026003 Mins Read
    Share Facebook Twitter Pinterest Copy Link LinkedIn Tumblr Email Telegram WhatsApp
    Follow Us
    Google News Flipboard
    Enhancing antitumour nanovaccine efficacy via integrated cholesterol modulation in situ
    Share
    Facebook Twitter LinkedIn Pinterest Email Copy Link


  • Moon, C. Y. et al. Dendritic cell maturation in cancer. Nat. Rev. Cancer 25, 225–248 (2025).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • You, Q. et al. A nanovaccine targeting cancer stem cells and bulk cancer cells for postoperative cancer immunotherapy. Nat. Nanotechnol. 20, 1298–1311 (2025).

  • Zhou, J. et al. STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity. Nature 643, 519–528 (2025).

  • Shapir Itai, Y. et al. Bispecific dendritic-T cell engager potentiates anti-tumor immunity. Cell 187, 375–389.e318 (2024).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Eweje, F. et al. Self-assembling protein nanoparticles for cytosolic delivery of nucleic acids and proteins. Nat. Biotechnol. (2025).

  • Meiser, P. et al. A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity. Cancer Cell 41, 1498–1515.e1410 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Plebanek, M. P. et al. A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression. Sci. Immunol. 9, eadi4191 (2024).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Calzada-Fraile, D. et al. Immune synapse formation promotes lipid peroxidation and MHC-I upregulation in licensed dendritic cells for efficient priming of CD8+T cells. Nat. Commun. 14, 6772 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Jacobs, C. F. et al. Cholesterol homeostasis and lipid raft dynamics at the basis of tumor-induced immune dysfunction in chronic lymphocytic leukemia. Cell Mol. Immunol. 22, 485–500 (2025).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Lei, K. et al. Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy. Nat. Biomed. Eng. 5, 1411–1425 (2021).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Xiao, J. et al. 25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages. Immunity 57, 1087–1104.e1087 (2024).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kropshofer, H. et al. Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes. Nat. Immunol. 3, 61–68 (2002).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Geels, S. N. et al. Interruption of the intratumor CD8+ T cell:Treg crosstalk improves the efficacy of PD-1 immunotherapy. Cancer Cell 42, 1051–1066.e1057 (2024).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Molino, N. M., Anderson, A. K., Nelson, E. L. & Wang, S. W. Biomimetic protein nanoparticles facilitate enhanced dendritic cell activation and cross-presentation. ACS Nano 7, 9743–9752 (2013).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Rosalia, R. A. et al. Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation. Eur. J. Immunol. 43, 2554–2565 (2013).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Belabed, M. et al. Cholesterol mobilization regulates dendritic cell maturation and the immunogenic response to cancer. Nat. Immunol. 26, 188–199 (2025).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Li, B. et al. Fueling sentinel node via reshaping cytotoxic T lymphocytes with a flex-patch for post-operative immuno-adjuvant therapy. Nat. Commun. 14, 2518 (2023).

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Shapiro, I. E. & Bassani-Sternberg, M. The impact of immunopeptidomics: from basic research to clinical implementation. Semin. Immunol. 66, 101727 (2023).

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Zeng, B. et al. Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapy. J. Clin. Invest. 128, 1971–1984 (2018).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Zhang, J. et al. Stimuli-responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy. Adv. Sci. 9, e2103444 (2022).

    Article 

    Google Scholar
     

  • Cruz, L. J. et al. Targeting nanoparticles to CD40, DEC-205 or CD11c molecules on dendritic cells for efficient CD8+ T cell response: a comparative study. J. Control. Release 192, 209–218 (2014).

    Article 
    CAS 
    PubMed 

    Google Scholar
     



  • Source link

    antitumour cholesterol Efficacy Enhancing Integrated Modulation nanovaccine situ
    Follow on Google News Follow on Flipboard
    Share. Facebook Twitter Pinterest LinkedIn Tumblr Email Copy Link
    tonirufai
    big tee tech hub
    • Website

    Related Posts

    Enhancing Identity Intelligence with Babel Street Match and Amazon OpenSearch

    April 19, 2026

    National Nanotechnology Coordination Office (NNCO)

    April 18, 2026

    how many galaxies and quasars are in the biggest high-res 3D map of our universe? – Physics World

    April 17, 2026
    Add A Comment
    Leave A Reply Cancel Reply

    Editors Picks

    GitLab Extends Agentic AI with New Automated Security Remediation, Pipeline Setup, and Delivery Analytics

    April 19, 2026

    AI’s impact on apparel beyond forecasting and fit

    April 19, 2026

    Enhancing antitumour nanovaccine efficacy via integrated cholesterol modulation in situ

    April 19, 2026

    Enhancing Identity Intelligence with Babel Street Match and Amazon OpenSearch

    April 19, 2026
    About Us
    About Us

    Welcome To big tee tech hub. Big tee tech hub is a Professional seo tools Platform. Here we will provide you only interesting content, which you will like very much. We’re dedicated to providing you the best of seo tools, with a focus on dependability and tools. We’re working to turn our passion for seo tools into a booming online website. We hope you enjoy our seo tools as much as we enjoy offering them to you.

    Don't Miss!

    GitLab Extends Agentic AI with New Automated Security Remediation, Pipeline Setup, and Delivery Analytics

    April 19, 2026

    AI’s impact on apparel beyond forecasting and fit

    April 19, 2026

    Subscribe to Updates

    Get the latest technology news from Bigteetechhub about IT, Cybersecurity and Big Data.

      • About Us
      • Contact Us
      • Disclaimer
      • Privacy Policy
      • Terms and Conditions
      © 2026 bigteetechhub.All Right Reserved

      Type above and press Enter to search. Press Esc to cancel.